Eye tracking en la Investigación médica Q1 2025

Background/Objectives: Gaze behaviours, such as fixation on single objects, and switching gaze between two objects are important for signaling messages, making choices or controlling a computer for children with cerebral palsy (CP) and similar movement disabilities. Observing these behaviours can be challenging for clinicians, with a lack of agreement on how they can be objectively quantified or rated. Methods: This study compares two methods of eliciting and observing gaze behaviours: a computer presentation using an eye tracker and an object presentati...Ver más

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Visuomotor integration (VMI) impairments are common in children with cerebral palsy (CP) and can impact performance of goal‐directed upper‐extremity tasks. VMI impairment is clinically assessed using the gold‐standard Beery‐Buktenica test, whereas research paradigms use computerized assessments incorporating eye and hand movement tracking with touchscreen displays. Immersive virtual reality (VR) may potentially enable more ecologically valid VMI assessments through the inclusion of 3D tasks and visual distractions. However, the potential of immersive VR ...Ver más

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• LSL

Purpose To assess eye movements during reading in individuals with central vision loss using eye-tracking technology and an ad-hoc calibration method. Materials and methods This pilot case control study included 17 participants (61.7 ± 8.8 years), 12 women and 5 men) and 17 controls, matched for age and sex. Two ad hoc computer-based tests were administered to analyze eye movements during a single-letter reading task and continuous reading task, measured using a 60 Hz eye-tracking device. Results Individuals with central vision loss showed differences fr...Ver más

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Introduction Parkinson’s disease (PD) presents with a variety of non-motor symptoms such as sleep disorders, hyposmia, pain, cognitive dysfunction, neuropsychiatric and autonomic symptoms. One of the most neglected motor symptoms is the impairment of eye movements, which occurs in 75% of PD patients. The aim of our study was to investigate the relationship between the severity of non-motor symptoms and the impairment of different types of eye movements. Methods We conducted a cross-sectional study with idiopathic PD patients in which non-motor symptoms ...Ver más

Adults with Down syndrome (DS) experience an increased risk of Alzheimer's disease (AD). Valid cognitive assessments for adults with DS with severe/profound intellectual disability (ID) are needed. It is unclear whether eye tracking is feasible for detecting AD in DS.

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Background/Objectives: Individuals with chronic agrammatic aphasia demonstrate real-time sentence processing difficulties at the lexical and structural levels. Research using time-sensitive measures, such as priming and eye-tracking, have associated these difficulties with temporal delays in accessing semantic representations that are needed in real time during sentence structure building. In this study, we examined the real-time processing effort linked to sentence processing in individuals with aphasia and neurotypical, age-matched control participants...Ver más

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Purpose Rett syndrome (RTT) is a rare neurodevelopmental disorder that mainly affects girls and women. Trofinetide is approved for the treatment of RTT in adults and children aged ≥2 years. To gain insight into experiences with RTT and effects of trofinetide treatment at different stages of RTT, interviews with caregivers of individuals with RTT were conducted upon their exit from the open-label trofinetide trials. Methods Interviews were conducted with caregivers of participants in the LILAC/LILAC-2 open-label extension trials of the phase 3 LAVENDER tr...Ver más

Objective: To investigate if eye tracking can support detection of covert voluntary eye movements and to compare these findings with a simultaneously performed clinical assessment according to the Coma Recovery Scale manual regarding visual stimuli.Design: Observational case series.Subjects: Twelve outpatients with prolonged disorders of consciousness recruited from the rehabilitation clinic of a regional rehabilitation unit.Method: Eye movements were recorded with a wearable eye tracker while performing 4 test items from the Coma Recovery Scale Revised....Ver más

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