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Conclusiones de la investigación médica sobre el eye tracking del primer trimestre de 2026

Eye tracking ha contribuido a la investigación en los ámbitos del cribado, el diagnóstico y la rehabilitación, al convertir el comportamiento de la mirada y de la pupila en señales clínicas cuantificables. Los estudios lo han utilizado para distinguir el deterioro cognitivo, comparar la visibilidad en endoscopias, evaluar la lectura en condiciones de maculopatía simulada y cuantificar los movimientos oculares en casos de estrabismo, demencia y tratamiento vestibular. En todas estas publicaciones, también ha ayudado a evaluar el rendimiento en tareas y a revelar estrategias compensatorias que resultan difíciles de captar con los métodos convencionales.

  1. 1. Development and validation of an eye-tracking-based cognitive impairment screening system for older adults in China: a cross-sectional study
  2. 2. Evaluation of Visibility With an Eye‐tracking System: Effectiveness of Narrow‐Band Imaging for Detecting Colorectal Adenoma and Serrated Lesions
  3. 3. A comprehensive study on detection of autism signs through visual attention features and machine learning models
  4. 4. Altered reality for visual rehabilitation: immersive assessment of reading and eye movements under simulated maculopathy
  5. 5. Effectiveness of changing stimulus frequency and intensity of sound for evaluating hearing by monitoring pupil responses
  6. 6. A novel eye‐tracking digital marker outperforms plasma biomarkers in detecting cognitive impairment
  7. 7. Eye tracking in virtual reality for neurorehabilitation: a narrative perspective on needs, challenges, and pathways beyond game engines
  8. 8. Real-world virtual reality task with eye tracking for the detection of residual visuospatial attention deficits: a pilot study
  9. 9. Virtual Reality Enables Rapid and Multi-Faceted Vision Screening in a Pilot Study
  10. 10. Small eye movements during convergence and divergence in individuals with intermittent exotropia
  11. 11. Explaining Autism Detection by Deep Learning Through Eye Gaze Patterns and Integrated Gradients
  12. 12. Advancing the total body skin exam through eye-tracking analysis: an observational pilot study
  13. 13. Keeping kids engaged: the effects of superimposed single-line cartoons on pattern reversal VEPs
  14. 14. Human accommodative visuomotor function is driven by contrast through ON and OFF pathways and is enhanced in myopia
  15. 15. The Automated Vestibular Rehabilitation System: Normative Data From a Machine Vision‐Guided Platform
  16. 16. Differences in Smooth Pursuit and Associated Saccades in Children With Two Common Types of Strabismus
  17. 17. Multimodal machine learning mobility assessment in Parkinson’s disease within supervised and unsupervised settings
  18. 18. Eye movement and reading behavior in older adults with dementia

Development and validation of an eye-tracking-based cognitive impairment screening system for older adults in China: a cross-sectional study

marzo 27, 2026Wei Si, XiaoHan Ma, Jiayue Lin, Ting Xu, Rui Wang, Aiyong Zhu & Wenting CaoInternational Journal of Medical Informatics

Background Global population ageing has rendered cognitive impairment a critical public health issue. Early screening is essential for timely intervention; however, traditional tools are limited by their reliance on professionals, cultural and educational biases, and high cost. Purpose This study aimed to develop and validate an unobtrusive, eye-tracking-based cognitive screening system (CIS-ET) for older adults in China, evaluating its efficacy in distinguishing between healthy controls (HCs), mild cognitive impairment (MCI), and Alzheimer’s disease (AD...

  • Tobii Pro Spark

Evaluation of Visibility With an Eye‐tracking System: Effectiveness of Narrow‐Band Imaging for Detecting Colorectal Adenoma and Serrated Lesions

marzo 21, 2026Moegi Mochizuki, Akiko Ohno, Shiori Tsubata, Ryutaro Sumi, Takahiro Shirakawa, Ryosuke Kaji, Yoko Jinbo, Yu Hada, Jun Miyoshi & Tadakazu HisamatsuDEN Open

ABSTRACT Objectives Image‐enhanced endoscopy may reduce colorectal cancer mortality by improving lesion detection. Narrow‐band imaging and texture and color enhancement imaging are widely used, but their diagnostic efficacy compared with white light imaging remains unclear. This study evaluated narrow‐band imaging and texture and color enhancement imaging versus white light imaging for detecting colorectal lesions, including adenomas and serrated lesions. Methods Images of 29 colorectal lesions (19 adenomas and 10 serrated lesions) measuring 10 mm or le...

  • Tobii Pro Nano
  • Tobii Pro Lab

A comprehensive study on detection of autism signs through visual attention features and machine learning models

marzo 14, 2026C Divya, D Anvitha, H N Naveen Kumar, Chandrashekar M Patil, S P Jhanavi & S HarshithaInformation and Communication Systems

Autism spectrum disorder (ASD) is characterized by difficulties in social interaction, verbal & nonverbal communication, and restricted & repetitive behaviors. Early detection of ASD is crucial for timely intervention, yet it remains a challenging task due to the heterogeneous nature of its manifestations. Growing evidence indicates that existing screening methods, such as the Modified Checklist for Autism in Toddlers, may lack adequate precision for the early identification of children with ASD in clinical settings. Eye tracking captures subtle differen...

  • Tobii Pro X60 / X120 / T60 / T120

Altered reality for visual rehabilitation: immersive assessment of reading and eye movements under simulated maculopathy

marzo 12, 2026Mattia Barbieri, Giulia A. Albanese, Davide Esposito, Monica Gori, Valentina Facchini, Silvio P. Sabatini & Giulio SandiniVirtual Reality

This study investigated how immersive simulation of central vision loss can be used to analyze reading behavior and compensatory oculomotor strategies. The goal was to assess whether gaze-contingent extended reality simulations can replicate clinically observed patterns and provide actionable insights for visual rehabilitation. Sixteen healthy participants performed MNREAD Acuity Chart Test under simulated bilateral maculopathy using a previously validated extended reality simulator of low vision conditions. Eye movement data were collected to quantify r...

  • Tobii VR

Effectiveness of changing stimulus frequency and intensity of sound for evaluating hearing by monitoring pupil responses

marzo 8, 2026Maria Paola Tramonti Fantozzi, Antonino Crivello, Davide La Rosa, Ottavia Marconi, Mario Milazzo, Diego Manzoni, Giacomo Fiacchini & Luca BruschiniBiomedical Signal Processing and Control

Assessing hearing through the pupil dilation response (PDR) to sound offers a non-invasive alternative to traditional audiometry, particularly useful in individuals unable to provide behavioral responses. However, reliable detection of sound-evoked PDRs is limited by variability in pupil size and the risk of false positives (Type I Errors). This study investigated whether pseudo-random variation of sound frequency and amplitude enhances the correspondence between PDR detection and sound perception in normal-hearing subjects. To improve reliability, epoch...

  • Tobii Pro Glasses 3
  • Tobii Pro Lab

A novel eye‐tracking digital marker outperforms plasma biomarkers in detecting cognitive impairment

marzo 1, 2026Yi Ling, Pan Sun, Chen Wang, Chen Wang, Guoping Peng, Yiying Wang, Xin Zhou, Zhengbo He, Binhui Liu, Jie Zhang, Jie Yu, Yujie Su, Kai Li, Kai Li, Tengfei Guo, Benyan Luo & Benyan LuoAlzheimer's & Dementia

INTRODUCTION: Detecting and monitoring cognitive performance in older adults is critical. In this study, we evaluated the validity of an eye-tracking tool in diagnosing cognitive impairment.METHODS: We recruited 119 cognitively unimpaired (CU) individuals and 157 cognitively impaired (CI) patients who completed digital eye-tracking tests and cognitive scales. Of them, 154, 120, 53, and 146 underwent plasma biomarker tests, amyloid-β positron emission tomography (Aβ-PET) scans, tau-PET scans, and magnetic resonance imaging (MRI) scans. The diagnostic perf...

  • SDK

Eye tracking in virtual reality for neurorehabilitation: a narrative perspective on needs, challenges, and pathways beyond game engines

marzo 1, 2026Minxin Cheng, Leanne Chukoskie & Leanne ChukoskieFrontiers in Virtual Reality

Virtual reality (VR) systems with integrated eye tracking offer a powerful way to study and support sensorimotor and cognitive function in neurorehabilitation. Eye movements provide a high-bandwidth window onto information processing, visuomotor integration, cognitive load, and affect, while immersive VR enables more ecologically valid yet controllable tasks spanning visual exploration, movement execution, object interaction, and social exchange. This narrative review synthesizes recent work on eye tracking in VR for neurorehabilitation, focusing on thre...

  • Tobii VR

Real-world virtual reality task with eye tracking for the detection of residual visuospatial attention deficits: a pilot study

marzo 1, 2026Jenni Uimonen, Liia Merzon, Sanna Villarreal, Siiri Laari, Anne Arola, Petra Ijäs, Marja Hietanen, Juha Salmi & Juha SalmiVirtual Reality

Traditional methods for evaluating spatial neglect or milder lateralized visuospatial attention deficits have been criticized for limited ecological relevance, narrow scope, and overly simplistic design. To address this, we introduce a new version of the Executive Performance in Everyday LIving (EPELI) virtual reality task. In the EPELI, participants perform cognitively demanding everyday chores in a home-like environment, while precise behavioral data capturing diverse aspects of visual attention is recorded. Fourteen healthy controls and ten right-side...

  • Tobii VR

Virtual Reality Enables Rapid and Multi-Faceted Vision Screening in a Pilot Study

marzo 1, 2026Margarita Labkovich, Andrew J. Warburton, Christopher P. Cheng, Oluwafeyikemi O. Okome, Vicente Navarro, Randal A. Serafini, Aly A. Valliani, Harsha Reddy & James ChelnisJournal of Clinical & Translational Ophthalmology

Background: Given global population growth and aging, it is imperative to prioritize early eye disease detection and treatment. However, as patient volume increases, providers are facing a shortage of workforce capacity, particularly in areas where eye doctors are already scarce, making it important to consider alternative innovative solutions that could help increase eye screening capabilities. This study compared virtual reality (VR) platform of vision screening exams that are used to evaluate ocular health, such as 24-2 perimetry, Ishihara tiles, and ...

  • Tobii VR

Small eye movements during convergence and divergence in individuals with intermittent exotropia

febrero 25, 2026Yoshihito Mochizuki, Akiko Kimura, Yoichi Okita, Akiko Masuda, Hiroyuki Kanda & Fumi GomiScientific Reports

We explored eye movement disorganization during convergence and divergence in individuals with intermittent exotropia (iXT), using a 300-Hz Tobii Pro Spectrum eye-tracking system. The participants comprised 20 patients with iXT, who were evaluated both before and three months after strabismus surgery, aged 15–40 years and 20 controls with orthophoria or horizontal exophorias of ≤ 8 prism diopters, exhibiting latent exo-deviations under dissociated viewing conditions. The participants alternated their gaze between a target at 30 cm and a monitor at 60 cm ...

  • Tobii Pro Spectrum

Explaining Autism Detection by Deep Learning Through Eye Gaze Patterns and Integrated Gradients

febrero 22, 2026Federica Colonnese, Francesco Di Luzio, Simone Colella & Massimo PanellaSmart Innovation Systems and Technologies Socially Aware and Responsible AI Applications

Autism Spectrum Disorder (ASD) is a complex neurodevelopmental condition marked by repetitive behaviors and challenges in communication and social interaction, with about 1 in 100 children affected. Diagnosis of ASD is challenging due to its reliance on subjective behavioral evaluations, but advanced technologies such as Deep Learning are being explored to improve early and accurate diagnoses. Among them, one promising application in ASD research is analyzing eye gaze patterns, as individuals with ASD often exhibit atypical behaviors, such as reduced eye...

  • Tobii Pro X60 / X120 / T60 / T120

Advancing the total body skin exam through eye-tracking analysis: an observational pilot study

febrero 22, 2026Dayna Gager, Calista Long, Amy Longenecker, Tierney Wallace, Jeffrey Miller, Okba Alenezy, Ling Rothrock & Matthew F. HelmArchives of Dermatological Research

Currently, there is no standardized method by which the total body skin exam (TBSE) is conducted in dermatologic clinics or taught in medical school or residency programs. There is limited data available that assesses efficiency and comprehensiveness of current exam methods on real patients. This study aimed to evaluate current TBSE procedures using novel eye-tracking technology and provide data to improve efficiency and quality of the skin exam. We conducted an observational pilot study by analyzing eye-tracking data obtained from 2 dermatologists durin...

  • Tobii Pro Glasses

Keeping kids engaged: the effects of superimposed single-line cartoons on pattern reversal VEPs

febrero 19, 2026Herman E. Talsma, Frank P. Hoeben, Maria M. van Genderen & Gerard C. de WitDocumenta Ophthalmologica

PurposeRecording reliable pattern-reversal VEPs (prVEPs) in children is challenging due to limited attention. Superimposing dynamic cartoons may enhance engagement, but their effects on the prVEP are unclear.MethodsFifteen healthy adults underwent prVEP testing under three conditions: (F) fixation on a central target (standard condition); (C) free viewing of a single-line cartoon superimposed onto the checkerboard pattern; and (M) a mixed condition, in which participants maintained fixation on the central target while the overlaid cartoon played. Eye mov...

  • Tobii Pro Spectrum
  • Open Source Presentation

Human accommodative visuomotor function is driven by contrast through ON and OFF pathways and is enhanced in myopia

febrero 18, 2026Urusha Maharjan, Hamed Rahimi-Nasrabadi, Sabina Poudel, Farzaneh Olianezhad, Jianzhong Jin, Mitchell W. Dul & Jose-Manuel AlonsoCell Reports

The human eyes are continuously adjusting refractive power, vergence angle, and pupil diameter when exploring the visual environment. Adjustment errors in these visuomotor functions reduce the stimulus contrast driving ON and OFF retinal pathways, and ON retinal pathways become weaker, slower, and less sensitive in refractive disorders such as myopia. Here, we demonstrate that, in addition to these sensory deficits, myopes also have deficits in visuomotor functions driven by ON and OFF pathways during lens accommodation. We show that humans with myopia h...

  • Tobii Pro Glasses 3
  • SDK
  • Open Source Presentation

The Automated Vestibular Rehabilitation System: Normative Data From a Machine Vision‐Guided Platform

febrero 8, 2026Erin Williams, Felipe Echeverri Tribin, Luis Rodriguez Diaz, Valerie Yunis, Devin Kennedy, Blaine Ayotte, Christopher McKenna, Odile Clavier & Michael HofferThe Laryngoscope

OBJECTIVE(S): Vestibular rehabilitation therapy (VRT) is an efficient treatment for dizziness and vertigo, but its accessibility remains limited. This study evaluates the feasibility and performance of a machine vision-based automated alternative-the Automated Vestibular Rehabilitation System (AVRS)-as a more accessible approach to delivering VRT.METHODS: Forty age- and sex-matched adults without balance disorders or recent head injury completed one standard VRT exercise, X1, in seated and standing positions using the AVRS, which tracked real-time head a...

    Differences in Smooth Pursuit and Associated Saccades in Children With Two Common Types of Strabismus

    febrero 3, 2026Elena Sanz, M. Pilar Aivar & Jaime TejedorInvestigative Ophthalmology & Visual Science

    Purpose: The main characteristics of smooth pursuit are well-described, but few studies have analyzed performance in strabismic patients, especially regarding differences between types of strabismus. In this study, we analyzed smooth pursuit eye movements of children with intermittent exotropia (IXT) or accommodative esotropia (AET), compared with age-matched controls.Methods: We included 58 children, aged between 4 and 13 years old (AET n = 24, IXT n = 18, and controls n = 16). After ophthalmological evaluation, eye movements were recorded using a Tobii...

    • Tobii Pro X3-120
    • Open Source Presentation

    Multimodal machine learning mobility assessment in Parkinson’s disease within supervised and unsupervised settings

    febrero 1, 2026Y. Celik, H. Kuduz, F. V. Engin, F. Kacar, E. Tarakci, L. T. Pearson-Noseworthy, J. Das, S. Stuart, W. L. Woo & A. GodfreyJournal of NeuroEngineering and Rehabilitation

    BackgroundMobility in people with Parkinson’s disease (PwPD) is strongly context-dependent. Clinic-based assessments provide only brief snapshots under controlled conditions and may not reflect everyday functional capacity. Wearable sensors enable continuous free-living monitoring, yet most studies use unimodal signals and simple threshold-based walking detection. Multimodal sensing, combining surface electromyography (sEMG) with inertial measurement units (IMUs), can offer a more complete picture of mobility in Parkinson’s disease (PD). Therefore, devel...

    • Tobii Pro Glasses

    Eye movement and reading behavior in older adults with dementia

    enero 30, 2026Ayano Inuyama, Motoshi Ouchi, Shigeki Hirano & Sayuri SuwaBMC Geriatrics

    BackgroundWith the rising number of patients with dementia, it is essential to develop support strategies that incorporate visual information. This study aimed to clarify differences in eye movement patterns when older adults with dementia read documents of varying difficulty, in order to identify strategies for enhancing readability and supporting comprehension.MethodsEye movements were measured using an eye tracker while nine older adults with dementia read documents. Each document had an original version and a revised version, designed to improve read...

    • Tobii Pro Glasses 2
    • Tobii Pro Lab
    1. 1. Development and validation of an eye-tracking-based cognitive impairment screening system for older adults in China: a cross-sectional study
    2. 2. Evaluation of Visibility With an Eye‐tracking System: Effectiveness of Narrow‐Band Imaging for Detecting Colorectal Adenoma and Serrated Lesions
    3. 3. A comprehensive study on detection of autism signs through visual attention features and machine learning models
    4. 4. Altered reality for visual rehabilitation: immersive assessment of reading and eye movements under simulated maculopathy
    5. 5. Effectiveness of changing stimulus frequency and intensity of sound for evaluating hearing by monitoring pupil responses
    6. 6. A novel eye‐tracking digital marker outperforms plasma biomarkers in detecting cognitive impairment
    7. 7. Eye tracking in virtual reality for neurorehabilitation: a narrative perspective on needs, challenges, and pathways beyond game engines
    8. 8. Real-world virtual reality task with eye tracking for the detection of residual visuospatial attention deficits: a pilot study
    9. 9. Virtual Reality Enables Rapid and Multi-Faceted Vision Screening in a Pilot Study
    10. 10. Small eye movements during convergence and divergence in individuals with intermittent exotropia
    11. 11. Explaining Autism Detection by Deep Learning Through Eye Gaze Patterns and Integrated Gradients
    12. 12. Advancing the total body skin exam through eye-tracking analysis: an observational pilot study
    13. 13. Keeping kids engaged: the effects of superimposed single-line cartoons on pattern reversal VEPs
    14. 14. Human accommodative visuomotor function is driven by contrast through ON and OFF pathways and is enhanced in myopia
    15. 15. The Automated Vestibular Rehabilitation System: Normative Data From a Machine Vision‐Guided Platform
    16. 16. Differences in Smooth Pursuit and Associated Saccades in Children With Two Common Types of Strabismus
    17. 17. Multimodal machine learning mobility assessment in Parkinson’s disease within supervised and unsupervised settings
    18. 18. Eye movement and reading behavior in older adults with dementia
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