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Eye tracking Insights in Q3 2025 Recherche médicale

Les publications de recherche médicale du 3e trimestre 2025 mettent en évidence le rôle significatif de la technologie de l'eye tracking dans divers contextes de santé. Qu'il s'agisse d'évaluer les troubles cognitifs chez les personnes âgées lors d'un entraînement à l'équilibre en réalité virtuelle, d'évaluer les effets de la chimiothérapie sur les mouvements oculaires ou d'aider au dépistage précoce des troubles du spectre autistique, l'eye tracking s'est avéré être un outil précieux. Cette technologie a fourni des données objectives et quantitatives, permettant de mieux comprendre le comportement des patients et l'évolution des maladies.

Visual attention during non-immersive virtual reality balance training in older adults with mild to moderate cognitive impairment: an eye-tracking study

Marcos Maldonado-Díaz, Gonzalo Jara-Vargas & Felipe González-SeguelFrontiers in Aging Neuroscience

Background: Older adults with cognitive impairment often present with balance deficits, reduced walking speed, and attentional difficulties—particularly in executive function. These challenges increase fall risk and complicate traditional rehabilitation approaches. Eye-tracking technology offers an objective way to evaluate attention by analyzing oculomotor behavior during tasks, but its use in clinical rehabilitation contexts is still limited. Objective: The aim of this study is to investigate visual attention using eye-tracking metrics during a non-im...

Eye Movement Impairment in Women Undergoing Chemotherapy

Milena Edite Casé de Oliveira, José Marcos Nascimento de Sousa, Gerlane Da Silva Vieira Torres, Ruanna Priscila Silva de Brito, Nathalia dos Santos Negreiros, Bianca da Nóbrega Tomaz Trombetta, Kedma Anne Lima Gomes Alexandrino, Waleska Fernanda Souto Nóbrega, Letícia Lorena Soares Silva Polimeni, Catarina Cavalcanti Braga, Cristiane Maria Silva de Souza Lima, Thiago P. Fernandes & Natanael Antonio dos SantosLecture Notes in Computer Science Social Robotics AI

The assessment of visual attention is important in visual and cognitive neuroscience, providing objective measures for researchers and clinicians. This study investigated the effects of chemotherapy on eye movements in women with breast cancer. Twelve women with breast cancer and twelve healthy controls aged between 33 and 59 years completed a visual search task, identifying an Arabic number among 79 alphabetic letters. Test duration, fixation duration, total fixation duration, and total visit duration were recorded. Compared to healthy controls, women w...

Medicine in novel technology and devices quantitative study and evaluation of ankle joint motor-cognitive dual-task post-stroke using eye-tracking technology

Yutong Feng, Yutong Feng, Hongbei Meng, Zihe Zhao, Xiaomeng Wang, Xiaomeng Wang, Xiaoxue Zhai, Xiaoxue Zhai, Yansong Hu, Guanyu Wang, Bo Peng, Bo Peng, Wenyu Yang, Xuemeng Li, Wenxin Tao, Shuo Gao, Yu Pan & Yu PanMedicine in Novel Technology and Devices

Dual-task ability is crucial for daily life, but sensory, cognitive, and motor impairments often reduce performance in patients, significantly impacting their quality of life. To evaluate and restore this ability, this study proposes an eye-tracking-based dual-task training system for ankle movement and cognition. The system is designed to capture and analyze real-time ankle and eye movement parameters, integrating these with traditional clinical scales to offer a multidimensional, objective, and quantitative evaluation standard. Reliability and criterio...

    A Novel Virtual Reality-Based System for Measuring Deviation Angle in Strabismus: A Prospective Study

    Jhih-Yi Lu, Jhih-Yi Lu, Yin-Cheng Liu, Jui-Bang Lu, Ming-Han Tsai, Wen-Ling Liao, Wen-Ling Liao, I-Ming Wang, Hui-Ju Lin, Hui-Ju Lin, Hui-Ju Lin, Yu-Te Huang & Yu-Te HuangDiagnostics

    Background/Objectives: To develop a new Virtual Reality (VR) system software for measuring ocular deviation in strabismus patients. Methods: This prospective study included subjects with basic-type exotropia (XT) and non-refractive accommodative esotropia (ET). Ocular deviation was measured using the alternate prism cover test (APCT) and two VR-based methods: target offset (TO) and a newly developed camera rotation (CR) method. Results: A total of 28 subjects were recruited (5 cases were excluded for preliminary testing and 5 for not meeting inclusion cr...

    • Tobii VR

    Understanding the Impact of Glaucoma Severities Through Virtual Reality Simulations

    Jesse W Grootjen, Sairam Narsimha Reddy Yadla & Sven Mayer

    Glaucoma is a visual impairment that presents a significant global challenge due to limited access to routine screenings. In this study, we explore glaucoma by creating a virtual-reality (VR) simulation of peripheral vision loss. Initial interviews (N=3) indicated that traditional darker peripheral visualizations do not accurately represent the experiences of individuals with glaucoma. Using simulation results and subsequent user testing (N=15) in VR, we demonstrate more nuanced methods of simulating varying severity of glaucoma that better match self-re...

    Visual Function in Alzheimer’s Disease: Current Understanding and Potential Mechanisms Behind Visual Impairment

    Isabel Lema, Juan Manuel Pías-Peleteiro, Maite López-López, Tania Alvite-Piñeiro, Tomás Sobrino & Uxía Regueiro

    Alzheimer’s disease (AD) is the leading cause of dementia worldwide and is becoming one of the most morbid diseases of this century. Recently, ocular research in AD has gained significance, as the eye, due to its close relationship with the brain, can reflect the presence of neurological disorders. Several studies have reported alterations in various ocular structures in AD, ranging from tear fluid to the retina. These changes, particularly in the retina and the optic nerve, along with cerebral atrophy affecting visual brain areas, may lead to visual dys...

    Early Objective ASD Screening System Based on Eye-Tracking and Machine Learning

    Daniel Fernandez-Lanvin, Gloria Acevedo-Diaz, Javier De Andres, Martin Gonzalez-Rodriguez & Sara Vecino

    The diagnosis of autism spectrum disorder (ASD) is still based on clinical observation, as there are no validated biomarkers for use in clinical practice. Although the first suspicions may appear as early as 12 months, the diagnosis may be delayed until 3 to 6 years. We propose an early screening procedure for autism starting at 9 months of age, which will allow paediatricians to objectively detect the presence of ASD risk indicators, facilitate immediate access to a specific preventive action program, and minimize the effects of the disorder. Our system...

    Saccadic eye movements in childhood: A pilot study comparing clinical eye tracker software and the NSUCO

    Alba Carrera, Carmen Bilbao, David P. Piñero, Josep-Oriol Casanovas-Marsal, Laura Remón Martín, María José López-de-la-Fuente & Rosa Hernández-Andrés

    PURPOSE: To explore differences in saccadic eye movements between children with oculomotor dysfunction and those in a control group across three age groups, using two assessment methods: the subjective Northeastern State University College of Optometry (NSUCO) Oculomotor test and objective analysis with the Tobii Eye X Eye Tracker (Tobii Eye X, Tobii, Stockholm, Sweden).METHODS: This study included 31 children (ages 7-13) diagnosed with oculomotor dysfunction and 16 age-matched children in the control group. Participants were divided into three age group...

      Optimising reaction‐time analysis in eye movement perimetry using pooled promptness distributions

      Ashwini Venkat Reddy Chanakya & Peter Bremen

      Reaction‐time measurements play a crucial role in assessing cognitive and sensory processing, with applications in functional clinical diagnostics such as eye‐movement perimetry (EMP) for the detection of glaucoma. However, reaction‐time distributions are typically right‐skewed, complicating statistical analysis and requiring large numbers of repetitions for reliable parameter estimation. One well‐known transformation to normalise reaction‐time distributions is taking their reciprocal, called ‘speed’ or ‘promptness’ (unit 1/s). Using the promptness trans...

      A review of eye-tracking technology and its application in stroke diagnosis and assessment

      Jun Zhang, Wei Kong, Ming Ma, Xi Yang, Weifeng Li & Aiguo SongMeasurement

      The eyes are the windows of the soul, providing essential information through eye movement. With the rapid development of eye-tracking technology (ETT), its application in health assessment, including diagnosing and treating neurological diseases, has expanded significantly. Stroke is a leading cause of adult death and disability worldwide, and studies have shown that eye movement information can serve as a quantitative indicator for stroke diagnosis and assessment. Despite significant research on ETT-based stroke diagnosis, a comprehensive review is sti...

      Reading Assessment and Eye Movement Analysis in Bilateral Central Scotoma Due to Age-Related Macular Degeneration

      Journal of Eye Movement Research

      This study investigates reading performances and eye movements in individuals with eccentric fixation due to age-related macular degeneration (AMD). Overall, 17 individuals with bilateral AMD (7 males; mean age 77.47 ± 5.96 years) and 17 controls (10 males; mean age 72.18 ± 5.98 years) were assessed for reading visual acuity (VA), reading speed (Minnesota low vision reading chart in Slovene, MNREAD-SI), and near contrast sensitivity (Pelli-Robson). Microperimetry (NIDEK MP-3) was used to evaluate preferential retinal locus (PRL) location and fixation sta...

      How does otitis media with effusion history affect spatial auditory processing and listening effort?

      Matan Yosef, Avital Trau-Margalit, Tami Harel-Arbeli & Riki Taitelbaum-Swead

      PurposeTo evaluate the impact of otitis media with effusion (OME) history on spatial auditory processing and listening effort (LE) in children with normal hearing thresholds.MethodsSeventeen children with a history of OME, whose hearing thresholds had returned to normal (mean age 7.8 years), and 22 age-matched controls (mean age 8 years) participated in the study. Assessments included audiometric evaluations, an adaptive speech-in-noise task under spatial and non-spatial conditions, Pupil Researchlometry to measure changes in Pupil Research dilation duri...

      Cognitive Workload During a Sustained Visual Attention Task in Middle-Aged and Older Adults With Persistent Symptoms After a Mild Traumatic Brain Injury

      Linda J. D’Silva, Sakher M. Obaidat, Peyton Huslig, Donald Keating, Prabhakar Chalise, Michael Rippee & Hannes Devos

      BackgroundIndividuals with prolonged symptoms after a mild traumatic brain injury (mTBI) report requiring more effort to complete complex and sustained activities. However, the relationship between cognitive workload and patient-reported symptoms is unclear.ObjectiveTo compare the cognitive workload between middle-aged and older adults with persistent symptoms after mTBI and controls during a sustained visual attention task and to examine the relationship between workload and patient-reported symptoms.MethodsIn this cross-sectional study, 48 adults (24 w...

      Deep learning quantifies pathologists’ visual patterns for whole slide image diagnosis

      Tianhang Nan, Song Zheng, Siyuan Qiao, Hao Quan, Xin Gao, Jun Niu, Bin Zheng, Chunfang Guo, Yue Zhang, Xiaoqin Wang, Liping Zhao, Ze Wu, Yaoxing Guo, Xingyu Li, Mingchen Zou, Shuangdi Ning, Yue Zhao, Wei Qian, Hongduo Chen, Ruiqun Qi, Xinghua Gao & Xiaoyu CuiIEEE Robotics and Automation Letters

      Based on the expertise of pathologists, the pixelwise manual annotation has provided substantial support for training deep learning models of whole slide images (WSI)-assisted diagnostic. However, the collection of pixelwise annotation demands massive annotation time from pathologists, leading to a high burden of medical manpower resources, hindering to construct larger datasets and more precise diagnostic models. To obtain pathologists’ expertise with minimal pathologist workloads then achieve precise diagnostics, we collect the image review patterns of...

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