Eye tracking medical research Q1 2026 insights

Background Global population ageing has rendered cognitive impairment a critical public health issue. Early screening is essential for timely intervention; however, traditional tools are limited by their reliance on professionals, cultural and educational biases, and high cost. Purpose This study aimed to develop and validate an unobtrusive, eye-tracking-based cognitive screening system (CIS-ET) for older adults in China, evaluating its efficacy in distinguishing between healthy controls (HCs), mild cognitive impairment (MCI), and Alzheimer’s disease (AD...Show more

• Tobii Pro Spark

ABSTRACT Objectives Image‐enhanced endoscopy may reduce colorectal cancer mortality by improving lesion detection. Narrow‐band imaging and texture and color enhancement imaging are widely used, but their diagnostic efficacy compared with white light imaging remains unclear. This study evaluated narrow‐band imaging and texture and color enhancement imaging versus white light imaging for detecting colorectal lesions, including adenomas and serrated lesions. Methods Images of 29 colorectal lesions (19 adenomas and 10 serrated lesions) measuring 10 mm or le...Show more

• Tobii Pro Nano
• Tobii Pro Lab

Autism spectrum disorder (ASD) is characterized by difficulties in social interaction, verbal & nonverbal communication, and restricted & repetitive behaviors. Early detection of ASD is crucial for timely intervention, yet it remains a challenging task due to the heterogeneous nature of its manifestations. Growing evidence indicates that existing screening methods, such as the Modified Checklist for Autism in Toddlers, may lack adequate precision for the early identification of children with ASD in clinical settings. Eye tracking captures subtle differen...Show more

• Tobii Pro X60 / X120 / T60 / T120

This study investigated how immersive simulation of central vision loss can be used to analyze reading behavior and compensatory oculomotor strategies. The goal was to assess whether gaze-contingent extended reality simulations can replicate clinically observed patterns and provide actionable insights for visual rehabilitation. Sixteen healthy participants performed MNREAD Acuity Chart Test under simulated bilateral maculopathy using a previously validated extended reality simulator of low vision conditions. Eye movement data were collected to quantify r...Show more

• Tobii VR

Assessing hearing through the pupil dilation response (PDR) to sound offers a non-invasive alternative to traditional audiometry, particularly useful in individuals unable to provide behavioral responses. However, reliable detection of sound-evoked PDRs is limited by variability in pupil size and the risk of false positives (Type I Errors). This study investigated whether pseudo-random variation of sound frequency and amplitude enhances the correspondence between PDR detection and sound perception in normal-hearing subjects. To improve reliability, epoch...Show more

• Tobii Pro Glasses 3
• Tobii Pro Lab

INTRODUCTION: Detecting and monitoring cognitive performance in older adults is critical. In this study, we evaluated the validity of an eye-tracking tool in diagnosing cognitive impairment.METHODS: We recruited 119 cognitively unimpaired (CU) individuals and 157 cognitively impaired (CI) patients who completed digital eye-tracking tests and cognitive scales. Of them, 154, 120, 53, and 146 underwent plasma biomarker tests, amyloid-β positron emission tomography (Aβ-PET) scans, tau-PET scans, and magnetic resonance imaging (MRI) scans. The diagnostic perf...Show more

• SDK

Virtual reality (VR) systems with integrated eye tracking offer a powerful way to study and support sensorimotor and cognitive function in neurorehabilitation. Eye movements provide a high-bandwidth window onto information processing, visuomotor integration, cognitive load, and affect, while immersive VR enables more ecologically valid yet controllable tasks spanning visual exploration, movement execution, object interaction, and social exchange. This narrative review synthesizes recent work on eye tracking in VR for neurorehabilitation, focusing on thre...Show more

• Tobii VR

Traditional methods for evaluating spatial neglect or milder lateralized visuospatial attention deficits have been criticized for limited ecological relevance, narrow scope, and overly simplistic design. To address this, we introduce a new version of the Executive Performance in Everyday LIving (EPELI) virtual reality task. In the EPELI, participants perform cognitively demanding everyday chores in a home-like environment, while precise behavioral data capturing diverse aspects of visual attention is recorded. Fourteen healthy controls and ten right-side...Show more

• Tobii VR

Background: Given global population growth and aging, it is imperative to prioritize early eye disease detection and treatment. However, as patient volume increases, providers are facing a shortage of workforce capacity, particularly in areas where eye doctors are already scarce, making it important to consider alternative innovative solutions that could help increase eye screening capabilities. This study compared virtual reality (VR) platform of vision screening exams that are used to evaluate ocular health, such as 24-2 perimetry, Ishihara tiles, and ...Show more

• Tobii VR

We explored eye movement disorganization during convergence and divergence in individuals with intermittent exotropia (iXT), using a 300-Hz Tobii Pro Spectrum eye-tracking system. The participants comprised 20 patients with iXT, who were evaluated both before and three months after strabismus surgery, aged 15–40 years and 20 controls with orthophoria or horizontal exophorias of ≤ 8 prism diopters, exhibiting latent exo-deviations under dissociated viewing conditions. The participants alternated their gaze between a target at 30 cm and a monitor at 60 cm ...Show more

• Tobii Pro Spectrum

Autism Spectrum Disorder (ASD) is a complex neurodevelopmental condition marked by repetitive behaviors and challenges in communication and social interaction, with about 1 in 100 children affected. Diagnosis of ASD is challenging due to its reliance on subjective behavioral evaluations, but advanced technologies such as Deep Learning are being explored to improve early and accurate diagnoses. Among them, one promising application in ASD research is analyzing eye gaze patterns, as individuals with ASD often exhibit atypical behaviors, such as reduced eye...Show more

• Tobii Pro X60 / X120 / T60 / T120

Currently, there is no standardized method by which the total body skin exam (TBSE) is conducted in dermatologic clinics or taught in medical school or residency programs. There is limited data available that assesses efficiency and comprehensiveness of current exam methods on real patients. This study aimed to evaluate current TBSE procedures using novel eye-tracking technology and provide data to improve efficiency and quality of the skin exam. We conducted an observational pilot study by analyzing eye-tracking data obtained from 2 dermatologists durin...Show more

• Tobii Pro Glasses

PurposeRecording reliable pattern-reversal VEPs (prVEPs) in children is challenging due to limited attention. Superimposing dynamic cartoons may enhance engagement, but their effects on the prVEP are unclear.MethodsFifteen healthy adults underwent prVEP testing under three conditions: (F) fixation on a central target (standard condition); (C) free viewing of a single-line cartoon superimposed onto the checkerboard pattern; and (M) a mixed condition, in which participants maintained fixation on the central target while the overlaid cartoon played. Eye mov...Show more

• Tobii Pro Spectrum
• Open Source Presentation

The human eyes are continuously adjusting refractive power, vergence angle, and pupil diameter when exploring the visual environment. Adjustment errors in these visuomotor functions reduce the stimulus contrast driving ON and OFF retinal pathways, and ON retinal pathways become weaker, slower, and less sensitive in refractive disorders such as myopia. Here, we demonstrate that, in addition to these sensory deficits, myopes also have deficits in visuomotor functions driven by ON and OFF pathways during lens accommodation. We show that humans with myopia h...Show more

• Tobii Pro Glasses 3
• SDK
• Open Source Presentation

OBJECTIVE(S): Vestibular rehabilitation therapy (VRT) is an efficient treatment for dizziness and vertigo, but its accessibility remains limited. This study evaluates the feasibility and performance of a machine vision-based automated alternative-the Automated Vestibular Rehabilitation System (AVRS)-as a more accessible approach to delivering VRT.METHODS: Forty age- and sex-matched adults without balance disorders or recent head injury completed one standard VRT exercise, X1, in seated and standing positions using the AVRS, which tracked real-time head a...Show more

Purpose: The main characteristics of smooth pursuit are well-described, but few studies have analyzed performance in strabismic patients, especially regarding differences between types of strabismus. In this study, we analyzed smooth pursuit eye movements of children with intermittent exotropia (IXT) or accommodative esotropia (AET), compared with age-matched controls.Methods: We included 58 children, aged between 4 and 13 years old (AET n = 24, IXT n = 18, and controls n = 16). After ophthalmological evaluation, eye movements were recorded using a Tobii...Show more

• Tobii Pro X3-120
• Open Source Presentation

BackgroundMobility in people with Parkinson’s disease (PwPD) is strongly context-dependent. Clinic-based assessments provide only brief snapshots under controlled conditions and may not reflect everyday functional capacity. Wearable sensors enable continuous free-living monitoring, yet most studies use unimodal signals and simple threshold-based walking detection. Multimodal sensing, combining surface electromyography (sEMG) with inertial measurement units (IMUs), can offer a more complete picture of mobility in Parkinson’s disease (PD). Therefore, devel...Show more

• Tobii Pro Glasses

BackgroundWith the rising number of patients with dementia, it is essential to develop support strategies that incorporate visual information. This study aimed to clarify differences in eye movement patterns when older adults with dementia read documents of varying difficulty, in order to identify strategies for enhancing readability and supporting comprehension.MethodsEye movements were measured using an eye tracker while nine older adults with dementia read documents. Each document had an original version and a revised version, designed to improve read...Show more

• Tobii Pro Glasses 2
• Tobii Pro Lab